Nr 3, 2022: Träning och rörelse

Precisionshälsa – framtidens friskvård är redan här

1) Vindefjärd AN, Alfvén T, Martling A. Precisionshälsa – av vikt för framtidens hälso- och sjukvård. Lakartidningen.se 2022-01-04. https://lakartidningen.se/opinion/debatt/2022/01/precisionshalsa-av-vikt-for-framtidens-halso-och-sjukvard

2) Forska!Sverige. Precisionshälsa – vägen framåt! Ett kunskapsunderlag från ”Agenda för hälsa och välstånd år 2022”. https://www.forskasverige.se/wp-content/uploads/Precisionshalsa-vagen-framat-Agenda-rapport-2022.pdf

3) Schüssler-Fiorenza Rose SM, Contrepois K, Moneghetti KJ, Zhou W, Mishra T, Mataraso S, Dagan-Rosenfeld O, Ganz AB, Dunn J, Hornburg D, Rego S, Perelman D, Ahadi S, Sailani MR, Zhou Y, Leopold SR, Chen J, Ashland M, Christle JW, Avina M, Limcaoco P, Ruiz C, Tan M, Butte AJ, Weinstock GM, Slavich GM, Sodergren E, McLaughlin TL, Haddad F, Snyder MP. A longitudinal big data approach for precision health. Nat Med. 2019 May;25(5):792-804. 

4) Viana JN, Edney S, Gondalia S, Mauch C, Sellak H, O’Callaghan N, Ryan JC. Trends and gaps in precision health research: a scoping review. BMJ Open. 2021 Oct 25;11(10):e056938.

5) CDC. Precision health: Improving health for each of us and all of us. Office of Science (OS), Office of Genomics and Precision Public Health. https://www.cdc.gov/genomics/about/precision_med.htm

Träning minskar giftigt ämne och skyddar mot depression

Blier P, El Mansari M. Serotonin and beyond: therapeutics for major depression. Philos Trans R Soc Lond B Biol Sci. 2013 Feb 25;368(1615):20120536. doi: 10.1098/rstb.2012.0536. PMID: 23440470; PMCID: PMC3638389.

  1. Moncrieff, J., Cooper, R.E., Stockmann, T. et al. The serotonin theory of depression: a systematic umbrella review of the evidence. Mol Psychiatry (2022). https://doi.org/10.1038/s41380-022-01661-0

  2. Valente-Silva P, Ruas JL. Tryptophan-Kynurenine Metabolites in Exercise and Mental Health. 2018 Mar 8. In: Spiegelman B, editor. Hormones, Metabolism and the Benefits of Exercise [Internet]. Cham (CH): Springer; 2017. PMID: 31314466.

  3. Erhardt S, Lim CK, Linderholm KR, Janelidze S, Lindqvist D, Samuelsson M, Lundberg K, Postolache TT, Träskman-Bendz L, Guillemin GJ, Brundin L. Connecting inflammation with glutamate agonism in suicidality. Neuropsychopharmacology. 2013 Apr;38(5):743-52. doi: 10.1038/npp.2012.248. Epub 2012 Dec 3. PMID: 23299933; PMCID: PMC3671988.

  4. Afridi R, Suk K. Neuroinflammatory Basis of Depression: Learning From Experimental Models. Front Cell Neurosci. 2021 Jul 2;15:691067. doi: 10.3389/fncel.2021.691067. PMID: 34276311; PMCID: PMC8283257.

  5. Hollis F, Pope BS, Gorman-Sandler E, Wood SK. Neuroinflammation and Mitochondrial Dysfunction Link Social Stress to Depression. Curr Top Behav Neurosci. 2022;54:59-93. doi: 10.1007/7854_2021_300. PMID: 35184261.

  6. Lasselin J, Benson S, Hebebrand J, Boy K, Weskamp V, Handke A, Hasenberg T, Remy M, Föcker M, Unteroberdörster M, Brinkhoff A, Engler H, Schedlowski M. Immunological and behavioral responses to in vivo lipopolysaccharide administration in young and healthy obese and normal-weight humans. Brain Behav Immun. 2020 Aug;88:283-293. doi: 10.1016/j.bbi.2020.05.071. Epub 2020 May 30. PMID: 32485294.

  7. Millischer V, Heinzl M, Faka A, Resl M, Trepci A, Klammer C, Egger M, Dieplinger B, Clodi M, Schwieler L. Intravenous administration of LPS activates the kynurenine pathway in healthy male human subjects: a prospective placebo-controlled cross-over trial. J Neuroinflammation. 2021 Jul 17;18(1):158. doi: 10.1186/s12974-021-02196-x. PMID: 34273987; PMCID: PMC8286561.

  8. Wang H, He Y, Sun Z, Ren S, Liu M, Wang G, Yang J. Microglia in depression: an overview of microglia in the pathogenesis and treatment of depression. J Neuroinflammation. 2022 Jun 6;19(1):132. doi: 10.1186/s12974-022-02492-0. PMID: 35668399; PMCID: PMC9168645.

  9. WHO guidelines on physical activity and sedentary behaviour. Geneva: World Health Organization; 2020. Licence: CC BY-NC-SA 3.0 IGO. file:///home/chronos/u-761653f24a2d763bed366e70aa2219c6a077f6c6/MyFiles/Downloads/9789240015128-eng.pdf

  10. Kang HJ, Voleti B, Hajszan T, Rajkowska G, Stockmeier CA, Licznerski P, Lepack A, Majik MS, Jeong LS, Banasr M, Son H, Duman RS. Decreased expression of synapse-related genes and loss of synapses in major depressive disorder. Nat Med. 2012 Sep;18(9):1413-7. doi: 10.1038/nm.2886. PMID: 22885997; PMCID: PMC3491115.

  11. Sleiman SF, Henry J, Al-Haddad R, El Hayek L, Abou Haidar E, Stringer T, Ulja D, Karuppagounder SS, Holson EB, Ratan RR, Ninan I, Chao MV. Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate. Elife. 2016 Jun 2;5:e15092. doi: 10.7554/eLife.15092. PMID: 27253067; PMCID: PMC4915811.

  12. Caplin A, Chen FS, Beauchamp MR, Puterman E. The effects of exercise intensity on the cortisol response to a subsequent acute psychosocial stressor. Psychoneuroendocrinology. 2021 Sep;131:105336. doi: 10.1016/j.psyneuen.2021.105336. Epub 2021 Jun 18. PMID: 34175558.

  13. Taniguchi K, Takano M, Tobari Y, Hayano M, Nakajima S, Mimura M, Tsubota K, Noda Y. Influence of External Natural Environment Including Sunshine Exposure on Public Mental Health: A Systematic Review. Psychiatry International. 2022; 3(1):91-113. https://doi.org/10.3390/psychiatryint3010008

Fyra träningsformer för bättre fysik – vilken passar dig?

Zhao M, Veeranki SP, Magnussen CG, Xi B. Recommended physical activity and all cause and cause specific mortality in US adults: prospective cohort study. BMJ. 2020 Jul 1;370:m2031.

  1. SVT. Styrketräning för 90-åringar hindrar demens.2016-02-15. https://www.svt.se/nyheter/vetenskap/styketraning-for-90-aringar-hindrar-demens

  2. Schott N, Johnen B, Holfelder B. Effects of free weights and machine training on muscular strength in high-functioning older adults. Exp Gerontol. 2019 Jul 15;122:15-24.

  3. Duke University. Benefits of Taking the Stairs. https://hr.duke.edu/wellness/exercise-fitness/take-stairs/benefits-taking-stairs

  4. Schoenfeld BJ, Aragon AA. How much protein can the body use in a single meal for muscle-building? Implications for daily protein distribution. J Int Soc Sports Nutr. 2018 Feb 27;15:10.

  5. Petruzzello SJ, Landers DM, Hatfield BD, Kubitz KA, Salazar W. A meta-analysis on the anxiety-reducing effects of acute and chronic exercise. Sports Medicine 1991;11(3),143-182.

  6. Howard VJ, McDonnell MN. Physical activity in primary stroke prevention: just do it! Stroke. 2015 Jun;46(6):1735-9.

  7. Luo L, Meng H, Wang Z, Zhu S, Yuan S, Wang Y, Wang Q. Effect of high-intensity exercise on cardiorespiratory fitness in stroke survivors: A systematic review and meta-analysis. Ann Phys Rehabil Med. 2020 Jan;63(1):59-68.

  8. Wang Y, Nie J, Ferrari G, Rey-Lopez JP, Rezende LFM. Association of Physical Activity Intensity With Mortality: A National Cohort Study of 403 681 US Adults. JAMA Intern Med. 2021 Feb 1;181(2):203-211.

  9. Wang C, Xing J, Zhao B, Wang Y, Zhang L, Wang Y, Zheng M, Liu G. The Effects of High-Intensity Interval Training on Exercise Capacity and Prognosis in Heart Failure and Coronary Artery Disease: A Systematic Review and Meta-Analysis. Cardiovasc Ther. 2022 Jun 9;2022:4273809.

  10. Boutcher SH. High-intensity intermittent exercise and fat loss. J Obes. 2011;2011:868305.

  11. Shiroma EJ, Lee IM. Physical activity and cardiovascular health: lessons learned from epidemiological studies across age, gender, and race/ethnicity. Circulation. 2010 Aug 17;122(7):743-52.

  12. Sharma A, Madaan V, Petty FD. Exercise for mental health. Prim Care Companion J Clin Psychiatry. 2006;8(2):106.

  13. Reed J, Ones DS. The effect of acute aerobic exercise on positive activated affect: A meta-analysis. Psychology of Sport and Exercise, 2006; 7(5), 477-514. https://doi.org/10.1016/j.psychsport.2005.11.003

  14. Gschwind YJ, Kressig RW, Lacroix A, Muehlbauer T, Pfenninger B, Granacher U. A best practice fall prevention exercise program to improve balance, strength / power, and psychosocial health in older adults: study protocol for a randomized controlled trial. BMC Geriatr. 2013 Oct 9;13:105.

  15. Heitkamp HC, Horstmann T, Mayer F, Weller J, Dickhuth HH. Gain in strength and muscular balance after balance training. Int J Sports Med. 2001 May;22(4):285-90. doi: 10.1055/s-2001-13819. PMID: 11414672.

  16. Chen HM, Wang HH, Chen CH, Hu HM. Effectiveness of a stretching exercise program on low back pain and exercise self-efficacy among nurses in Taiwan: a randomized clinical trial. Pain Manag Nurs. 2014 Mar;15(1):283-91.

  17. Opplert J, Babault N. Acute Effects of Dynamic Stretching on Muscle Flexibility and Performance: An Analysis of the Current Literature. Sports Med. 2018 Feb;48(2):299-325. doi: 10.1007/s40279-017-0797-9. PMID: 29063454.

  18. Choi W. Effect of 4 Weeks of Cervical Deep Muscle Flexion Exercise on Headache and Sleep Disorder in Patients with Tension Headache and Forward Head Posture. Int J Environ Res Public Health. 2021 Mar 25;18(7):3410.

  19. Kizhakkeveettil A, Whedon J, Schmalzl L, Hurwitz EL. Yoga for Quality of Life in Individuals With Chronic Disease: A Systematic Review. Altern Ther Health Med. 2019 Jan;25(1):36-43.

Överrörlighet och kopplingen till ångest och mag-tarmbesvär

1) Csecs JLL, Iodice V, Rae CL, Brooke A, Simmons R, Quadt L, Savage GK, Dowell NG, Prowse F, Themelis K, Mathias CJ, Critchley HD, Eccles JA. Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain. Front Psychiatry. 2022 Feb 2;12:786916.

2) Patients with Ehlers-Danlos syndrome-hypermobility type (EDS-HT) have increased prevalence of gastrointestinal (GI) symptoms, particularly reflux and dyspepsia. https://pubmed.ncbi.nlm.nih.gov/27683076/

3) Sharp HEC, Critchley HD, Eccles JA. Connecting brain and body: Transdiagnostic relevance of connective tissue variants to neuropsychiatric symptom expression. World J Psychiatry. 2021 Oct 19;11(10):805-820.

4) Pailhez G, Rosado S, Bulbena Cabré A, Bulbena A. Joint hypermobility, fears, and chocolate consumption. J Nerv Ment Dis. 2011 Nov;199(11):903-6.

5) Javadi Parvaneh V, Modaress S, Zahed G, Rahmani K, Shiari R. Prevalence of generalized joint hypermobility in children with anxiety disorders. BMC Musculoskelet Disord. 2020 Jun 2;21(1):337.

6)Do T, Diamond S, Green C, Warren M. Nutritional Implications of Patients with Dysautonomia and Hypermobility Syndromes. Curr Nutr Rep. 2021 Dec;10(4):324-333.

7) Brockway L. Gastrointestinal problems in hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders. Ehler-Danlos Support UK. https://www.ehlers-danlos.org/information/gastrointestinal-problems-in-hypermobile-ehlers-danlos-syndrome-and-hypermobility-spectrum-disorders

8) Zhou W, Zikos T, Neshatian L, Nguyen L. S0476 high prevalence of methane predominant small bowel bacterial overgrowth and constipation in patients with hypermobile Ehlers-Danlos syndrome. Off J Am Coll Gastroenterol ACG. 2020;115:S238.